{"publisher":{"name":"MediaBias News","url":"https://mediabias.news","methodology":"https://mediabias.news/methodology","editorialPrinciples":"https://mediabias.news/editorial-principles","corrections":"https://mediabias.news/corrections"},"scoreGuide":{"trust":"How well corroborated and evidenced the source reporting is. 0-100, higher is better.","critic":"Craft quality of the source journalism: context, balance, fact vs comment. 0-100, higher is better.","hype":"How far the source presentation runs ahead of substance. 0-100, LOWER IS BETTER.","scope":"Scores assess the original reporting this article was written from, not the truth of the underlying event and not the quality of this write-up."},"assessmentGuide":{"type":"coverage-and-source-reporting-analysis","factCheck":{"status":"not-performed","note":"Media Bias News compares coverage and scores the source reporting. It does not currently publish a ClaimReview verdict on whether the underlying event or claim is true."},"sourceFactuality":{"note":"Factuality values describe published ratings of the outlets that covered the story. They are not a factuality verdict on this story or its claims."}},"story":{"id":"https://mediabias.news/tech/crispr-edited-beagles-lack-main-dog-allergen-study-finds","slug":"crispr-edited-beagles-lack-main-dog-allergen-study-finds","url":"https://mediabias.news/tech/crispr-edited-beagles-lack-main-dog-allergen-study-finds","title":"CRISPR-edited beagles lack main dog allergen, study finds","subtitle":"Scientists at Kindred Companion Sciences used gene editing to remove the protein that causes most dog allergies in humans","excerpt":"Researchers used CRISPR to edit a gene in beagles, producing two puppies without the main allergy-causing protein. The study, published in the CRISPR Journal, found the dogs' saliva and fur lacked the protein, and a scientist with severe allergies showed no reaction. Ethical concerns about shelter adoptions were raised.","category":"Science & Tech","area":"United States","publishedAt":"2026-08-05T15:45:44.524Z","sourceReportedAt":"2026-08-05T13:41:33.000Z","updatedAt":"2026-08-05T15:45:44.524Z","readTime":"5 min read","scores":{"trust":74,"critic":95,"hype":15,"notes":{"trust":"Trust 74: multiple named sources, CRISPR Journal citation, specific dates and locations, but no independent outlets beyond the full report.","critic":"Critic 95: clear relevance, many expert quotes, specific facts, and outlined future uncertainties.","hype":"Hype 15: measured language, no exaggerated claims, headline matches article content."}},"tags":["#GeneEditing","#CRISPR","#DogAllergies","#Biotechnology","#AnimalResearch"],"entities":["Kindred Companion Sciences","Matt Walker","Alfie","Bailey","Arthur Caplan","CRISPR Journal"],"body":[{"type":"key_takeaways","items":["Scientists at Kindred Companion Sciences used CRISPR to edit a gene in beagles, creating two puppies named Alfie and Bailey without the main allergy-causing protein in dogs.","The study, published in the CRISPR Journal, found the beagles' saliva and fur lacked the protein, and geneticist Matt Walker, who has severe dog allergies, experienced no reaction when exposed to them.","Bioethicist Arthur Caplan warned the technology could discourage adoption of shelter animals, while the long-term health effects of the genetic edit remain unclear.","The technique has not yet been tested on other dog breeds or commercialised, and further research is needed to confirm its safety and effectiveness."]},{"type":"paragraph","text":"Scientists at Kindred Companion Sciences, a New York-based biotech company, used CRISPR gene editing to produce two beagle puppies without the main protein that causes dog allergies in humans. The puppies, named Alfie and Bailey, were born in September 2024 after researchers edited the genetic code in dog skin cells to switch off the gene responsible for the allergy-causing protein. The edited genetic code was then transferred into eggs implanted in a beagle surrogate."},{"type":"paragraph","text":"Tests on the puppies' saliva and fur showed no signs of the allergy-causing protein. Geneticist Matt Walker, who co-founded Kindred Companion Sciences and has severe dog allergies, tested the beagles on himself. He reported no allergic reaction when exposed to Alfie and Bailey, unlike his reactions to other dogs, including breeds marketed as hypoallergenic. The study was published in the CRISPR Journal on 4 September 2026."},{"type":"paragraph","text":"Walker, who now lives with Bailey in New York, described the experience as \"a mix of relief and awe and gratitude that it worked.\" He noted that the gene edited in the beagles is present in all dogs, and the company plans to test the technique on other breeds and service animals. However, experts not involved in the study cautioned that the long-term health effects of the genetic edit are unknown, and further testing is needed to confirm the technique's safety and effectiveness across a broader population."},{"type":"heading","text":"What the coverage left out"},{"type":"paragraph","text":"None of the digests from left-rated outlets mentioned the ethical concerns raised by bioethicist Arthur Caplan about the potential impact on shelter adoptions. The right-rated digest also omitted this detail. The left-rated digests did not include the name of the CRISPR Journal, where the study was published, though they noted the use of CRISPR technology. The right-rated digest did not mention the journal or the need for long-term health monitoring of the puppies."}],"basedOn":[{"sourceName":"The Independent Online","url":"https://dailyindependent.com/national/gene-edited-beagles-may-offer-a-future-option-for-people-with-dog-allergies/article_241918bb-fdbf-560b-b96a-8cac48315397.html","headline":"Gene-edited beagles may offer a future option for people with dog allergies","angle":"","publishedAt":"2026-08-05T13:41:33.000Z"},{"sourceName":"Yankton Press & Dakotan","url":"https://yankton.net/news/national_ap/article_a1267d9d-e234-5b12-a37a-61c07b54dbf6.html","headline":"Gene-edited beagles may offer a future option for people with dog allergies","angle":"","publishedAt":"2026-08-05T13:41:33.000Z"},{"sourceName":"Mankato Free 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They noted that the gene edit was performed using CRISPR, a Nobel Prize-winning technique, and that the edited puppies lacked the main allergy-causing protein in dogs. None of the digests mentioned the ethical concerns raised by bioethicist Arthur Caplan or the potential impact on shelter adoptions."],"centre":["The six centre-rated digests all led on the creation of hypoallergenic beagles using CRISPR gene editing. They included the names of the puppies, the absence of the allergy-causing protein in their saliva and fur, and the involvement of Kindred Companion Sciences. The full report from My Mother Lode, a centre-rated outlet, provided additional detail: it quoted bioethicist Arthur Caplan warning that the technology could discourage adoption of shelter animals, and noted that the gene edit is rare but occurs naturally in some dogs.","The My Mother Lode report also included a direct quote from geneticist Matt Walker describing his personal experience with Bailey, and mentioned that the study was published in the CRISPR Journal. It carried the ethical concerns raised by Caplan and the need for further testing to confirm the technique’s safety and broader applicability."],"right":["The single right-rated digest from Breitbart led on the creation of hypoallergenic beagles using gene editing. It included the names of the puppies and the absence of the allergy-causing protein but did not mention the ethical concerns raised by Arthur Caplan or the potential impact on shelter adoptions. 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