{"publisher":{"name":"MediaBias News","url":"https://mediabias.news","methodology":"https://mediabias.news/methodology","editorialPrinciples":"https://mediabias.news/editorial-principles","corrections":"https://mediabias.news/corrections"},"scoreGuide":{"trust":"How well corroborated and evidenced the source reporting is. 0-100, higher is better.","critic":"Craft quality of the source journalism: context, balance, fact vs comment. 0-100, higher is better.","hype":"How far the source presentation runs ahead of substance. 0-100, LOWER IS BETTER.","scope":"Scores assess the original reporting this article was written from, not the truth of the underlying event and not the quality of this write-up."},"assessmentGuide":{"type":"coverage-and-source-reporting-analysis","factCheck":{"status":"not-performed","note":"Media Bias News compares coverage and scores the source reporting. It does not currently publish a ClaimReview verdict on whether the underlying event or claim is true."},"sourceFactuality":{"note":"Factuality values describe published ratings of the outlets that covered the story. They are not a factuality verdict on this story or its claims."}},"story":{"id":"https://mediabias.news/health/shingrix-vaccine-may-reduce-heart-disease-and-dementia-risk","slug":"shingrix-vaccine-may-reduce-heart-disease-and-dementia-risk","url":"https://mediabias.news/health/shingrix-vaccine-may-reduce-heart-disease-and-dementia-risk","title":"Shingrix vaccine may reduce heart disease and dementia risk","subtitle":"A study suggests the recombinant shingles vaccine offers protection against cardiovascular events and cognitive decline.","excerpt":"Research indicates the Shingrix vaccine may provide protection against cardiovascular events and dementia. A study found a reduced risk of heart disease and cognitive decline in those vaccinated compared to an older vaccine.","category":"Health","area":null,"publishedAt":"2026-08-26T09:45:40.497Z","sourceReportedAt":"2026-08-26T09:00:38.000Z","updatedAt":"2026-08-26T09:45:40.497Z","readTime":"4 min read","scores":{"trust":60,"critic":65,"hype":45,"notes":{"trust":"Two full reports and two digests cite a study linking the recombinant shingles vaccine to reduced cardiovascular events and dementia.","critic":"Two full reports and four digests cover the study, with one digest irrelevant to the core findings.","hype":"Headlines and digests use terms like 'game-changer' and 'protecting both heart and brain'."}},"tags":["#ShinglesVaccine","#Shingrix","#CardiovascularHealth","#DementiaRisk","#PublicHealth"],"entities":["Shingrix","Zostavax","Maxime Taquet","Kaley Hayes","Brown University","University of Oxford"],"body":[{"type":"key_takeaways","items":["The recombinant shingles vaccine Shingrix may offer protection against cardiovascular events, according to a study.","The vaccine was linked to a 24% lower risk of dementia in older adults in one analysis.","Researchers suggest the vaccine's adjuvant may cause beneficial changes in immune cells and the vascular endothelium.","The apparent cardiovascular benefit was mainly observed in the first 3.5 years after vaccination."]},{"type":"paragraph","text":"A study suggests that the recombinant shingles vaccine, Shingrix, may offer protection against cardiovascular events and dementia. Research published in Nature Medicine indicated that individuals vaccinated with Shingrix experienced a nine percent reduction in cardiovascular disease burden over seven years compared to those who received the older Zostavax vaccine. This benefit was observed across several conditions, including a 10% reduction in coronary heart disease, a 12% reduction in heart failure, and a seven percent reduction in atrial fibrillation. Stroke outcomes were less clear, though a 12% lower burden was noted in men receiving Shingrix."},{"type":"paragraph","text":"Another analysis, drawing on Medicare data and health records of over 500,000 adults, linked the Shingrix vaccine to a 24% lower risk of dementia in older adults. This study compared patients who received at least one dose of Shingrix with unvaccinated individuals over a four-year follow-up period. Dementia developed in 18.8% of vaccinated participants compared to 24.6% of those who were not vaccinated. The study authors noted that while the findings suggest a link, they cannot definitively prove cause and effect, and further clinical trials are needed."},{"type":"heading","text":"Disagreement on dementia risk reduction"},{"type":"paragraph","text":"One study reported a 24% lower risk of dementia in older adults who received the Shingrix vaccine. Another report mentioned that the same vaccine group had a 17% lower risk of dementia over the follow-up period compared to the live vaccine group."},{"type":"heading","text":"What the coverage left out"},{"type":"paragraph","text":"None of the centre-rated or right-rated reports mentioned the specific methodology used by Inside Precision Medicine, which involved comparing groups vaccinated in 2017 and 2018. The centre-rated reports did not mention the specific funding source for the Science Daily study, which was GlaxoSmithKline, the manufacturer of Shingrix. No reports mentioned the potential for repeated vaccination at regular intervals as suggested by the researchers in Inside Precision Medicine."}],"basedOn":[{"sourceName":"Diari de la Discapacitat","url":"https://diarideladiscapacitat.cat/un-estudi-amb-mes-de-500-000-gent-gran-vincula-la-vacuna-de-lherpes-zoster-amb-un-menor-risc-de-demencia","headline":"A Study of More than 500,000 Elderly People Links the Herpes Zoster Vaccine to a Lower Risk of Dementia","angle":"","publishedAt":"2026-08-26T09:24:48.000Z"},{"sourceName":"Inside Precision Medicine","url":"https://insideprecisionmedicine.com/topics/patient-care/recombinant-shingles-vaccine-linked-to-lower-cardiovascular-events","headline":"Recombinant Shingles Vaccine Linked to Lower Cardiovascular Events","angle":"","publishedAt":"2026-08-26T09:00:38.000Z"},{"sourceName":"NewScientist","url":"https://newscientist.com/article/2586346-shingles-vaccine-may-lower-risk-of-stroke-and-heart-failure","headline":"Shingles vaccine may lower risk of stroke and heart failure","angle":"","publishedAt":"2026-08-26T09:00:00.000Z"},{"sourceName":"STAT","url":"https://statnews.com/2026/08/26/shingles-vaccine-shingrix-reduces-heart-disease-dementia-risk-oxford-study","headline":"Newer shingles vaccine linked to lower heart disease risk, ‘natural experiment’ shows","angle":"","publishedAt":"2026-08-26T09:00:00.000Z"},{"sourceName":"The News","url":"https://thenews.com.pk/latest/1413662-scientists-find-clue-to-lower-dementia-risk-in-older-adults-through-new-game-changer-vaccine","headline":"Scientists find clue to lower dementia risk in older adults through new ‘game-changer’ vaccine","angle":"","publishedAt":"2026-08-26T08:56:00.000Z"},{"sourceName":"La Razón","url":"https://larazon.es/sociedad/estudio-mas-500000-mayores-detecta-menos-casos-demencia-vacunados-herpes-zoster_202608266a8e8119ae2f3735da14377f.html","headline":"A Study of More than 500,000 Older People Detects Fewer Cases of Dementia Among Herpes Zoster Vaccinated","angle":"","publishedAt":"2026-08-26T06:00:57.000Z"},{"sourceName":"Science Daily","url":"https://sciencedaily.com/releases/2026/08/260823015013.htm","headline":"Shingles vaccine linked to 24% lower dementia risk","angle":"","publishedAt":"2026-08-25T12:49:26.026Z"},{"sourceName":"Medscape","url":"https://medscape.com/viewarticle/shingles-young-australians-prompts-vaccination-discussion-2026a1000tjs","headline":"Shingles in Young Australians Prompts Vaccination Discussion","angle":"","publishedAt":"2026-08-25T00:00:00.000Z"}],"analysis":{"distribution":{"percent":{"left":0,"centre":67,"right":33},"count":{"left":0,"centre":4,"right":2},"totalSources":8,"untracked":2,"rated":6,"observedAt":"2026-08-26T09:58:43.061Z"},"lifecycle":{"state":"developing","lastCheckedAt":"2026-08-26T11:45:10.674Z","closedAt":null,"checks":8,"changes":0,"reopened":false},"framing":{"left":[],"centre":["Centre-rated reports led on the potential cardiovascular benefits of the Shingrix vaccine. Inside Precision Medicine highlighted that the vaccine may offer protection against cardiovascular events, citing a nine percent reduction in cardiovascular disease burden and specific reductions in coronary heart disease, heart failure, and atrial fibrillation. Science Daily focused on the vaccine's link to a 24% lower risk of dementia, presenting it as adding to evidence of vaccination's neuroprotective benefits. New Scientist also noted the potential for reduced stroke and heart failure risk, while STAT reported on the vaccine's link to lower heart disease and dementia risk, calling it a 'natural experiment' by Oxford researchers."],"right":["Right-rated reports focused on the dementia risk reduction associated with the Shingrix vaccine. The News described the vaccine as a 'game-changer' for lowering dementia risk in older adults. 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