Topic
clinicaltrials
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HealthAstraZeneca COPD drug shows trial success, sales forecast raised
AstraZeneca has released full results from two late-stage trials of its experimental COPD drug, tozorakimab. The data indicates the drug reduced flare-ups by up to 43% in various patient groups and has led AstraZeneca to raise its peak annual sales forecast for the drug to over $5 billion.
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HealthAI-designed drug rentosertib shows potential to reduce biological age markers
Insilico Medicine's AI-designed drug rentosertib, tested in a small study for idiopathic pulmonary fibrosis, indicated a reduction in biological age markers. Six independent aging clocks suggested patients treated with the drug appeared biologically younger than those on placebo, with the largest effect seen in the 30mg twice-daily arm.
4 min readTrust 50 · Craft 65 · Hype 45
HealthModerna and Merck report melanoma vaccine trial success in phase three
Merck and Moderna announced positive phase three trial results for a personalised mRNA cancer vaccine combined with Keytruda, reducing melanoma recurrence and spread in high-risk patients. The treatment met its primary goal, with stock prices rising on the news. Further data will determine regulatory approval timelines.
4 min readTrust 85 · Craft 85 · Hype 15
Science & Tech · United KingdomFridge-free tetanus-diphtheria vaccine succeeds in first human trial
A UK-led trial of a tetanus-diphtheria vaccine that does not require refrigeration has reported 100% protective antibody levels in all participants. The vaccine, SPVX02, remained stable at 30°C for at least two years, addressing cold-chain failures that waste millions of doses annually.
United Kingdom4 min readTrust 86 · Craft 80 · Hype 18